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Molecular Biology Product Catalog

Malaria

Release date:2022-06-24

Plasmodium parasites occur on infectious diseases caused by the human body.Infection occurs by malaria mosquito bites or feeding into blood from people with Plasmodium parasites.Different Plasmodium species cause P. vivax, P. vivax, P. falciparum, and P. ovale.This disease is mainly manifested as periodic and regular attacks, systemic chills, fever, excessive sweating, after long-term multiple attacks, can cause anemia and splenomegaly.Malaria is a parasitic disease caused by Plasmodium, which occurs more frequently in summer and autumn.In tropical and subtropical areas, the disease can occur throughout the year, and it is prone to epidemic.


Malaria is now almost extinct in cities and towns, but it is still endemic in many rural areas, especially in Africa, Latin America, and Southeast Asia.

Malaria is widely prevalent around the world. According to the World Health Organization, 92 countries and regions still have high and moderate epidemics, with 150 million people occurring annually and 2 million people dying from malaria.Before the liberation of China, especially in the south, the fatality rate was very high.After liberation, malaria prevention and control institutions have been established across the country, and extensive malaria prevention and research work have been carried out, and the incidence of malaria has decreased significantly.

There are four types of human malaria parasites: Plasmodium vivax (P.vivax),Plasmodium falciparum (P.falciparum), Plasmodium triax (P.malarial), and Plasmodium ovale (P.ovale).Previously, two species were common, and only a few cases of P. ovale were found.There are more than 100 species of malaria parasites in various vertebrates (mainly birds, rats, and apes), and the primate parasites alone can infect humans.

Plasmodium develops in two stages: asexual proliferation in humans, the beginning of sexual proliferation, and sexual proliferation and spore proliferation in mosquitoes.The life histories of the four Plasmodium species were largely identical.

Malaria is a disease caused by Plasmodium sp.Since there is no significant inflammatory response surrounding the parasitic liver cells, it is speculated that the infrared phase does not cause the host clinical symptoms.From the fact that the onset of malaria symptoms is consistent with the maturity time of Plasmodium red, it is believed that Plasmodium takes hemoglobin in red blood cells and produces metabolites and malaria pigments. When the schizosons mature, the red blood cells swell and enter the blood flow together with the merozoites, which acts on the body temperature regulation center to cause fever and other related symptoms.Different kinds of schizosome proliferation time is inconsistent, and clinical attack cycle is inconsistent, general vivax malaria and P. ovale for alternate day, three days between two days, falciparum malaria due to protozoan development is not neat, hence make irregular attacks, and P. falciparum erythrocyte cleavsome in visceral microvessels, easy to cause visceral damage.

The onset of malaria is also related to the number of protoplasma parasites, resulting in the minimum number of internal protoplasma parasites per cubic millimeter required for fever, called the fever threshold.Plasmodium vivax is 10 to 500; falciparum malaria 500 to 1300; and malaria malaria 140. The magnitude of the change is related to the individual's tolerance and immunity.


Malaria is caused by Plasmodium, which medically divides into four categories: P. vivax, Plasmodium trii, Plasmodium ovale, and P. dium falciparum.Malaria caused by P. vivax and P. Plasmodium ovale, occurring every other day, is called P. vivax.Malaria caused by Plasmodium malaria is occurs every two days.Malaria caused by Plasmodium falciparum is called falciparum malaria, it has frequent attacks, irregular, severe often have ventilation, coma and other diseases, if not treated in time, the patient can die in a short time.The vector of malaria is Anopheles, which inhale the blood of malaria disease, and then bite healthy people, it will bring the Plasmodium in its saliva into the blood of healthy people, making healthy people sick.Therefore, to prevent malaria to seize the active treatment of the source of infection (patients), completely kill anopheles mosquitoes and do a good job in personal protection of these three basic links.

1. Actively treat the source of infection.Commonly used drugs are mainly hydroxyquipiperate, pyrimethamine, cough dine of phosphate and so on.In addition, Changshan, Artemisia annua, Bupleurum and other traditional Chinese medicine for malaria effect is also very good.The above drugs should be used by doctors according to the type of Plasmodium and the severity of the disease, the dosage and usage are not easy to master, do not eat them themselves.In addition, the patient should be treated off-stop, treating those who had had malaria in the previous year with primaquinoline for 8 days to prevent relapse.

2. Eliminate anopheles mosquitoes completely.The main measures are to improve environmental sanitation, including removing sewage, reforming the rice field irrigation method, developing fish farming in ponds and rice fields, and often spraying mosquito medicine in indoor and animal sheds.

3. Take your personal protection well.Including personal hygiene, not sleeping outdoors in summer, sleep, it is best to hang a mosquito net, go out during the day, in the bare part of the body to avoid mosquito bites.

It is summer, and malaria outbreaks in many parts of the world. While doing personal protection, early detection and diagnosis and treatment should be achieved. Hunan Runmei Gene Technology Co., Ltd., developed for a variety of Plasmodium detection kit, vivax malaria, ovoid malaria dual nucleic acid detection kit fluorescence PCR method, Plasmodium, vivax malaria, falciparum triple nucleic acid detection kit fluorescence PCR method, Plasmodium nucleic acid detection kit, and malaria test kit colloid gold . These kits are of great significance for the early detection of Plasmodium pathogens, which have recently obtained EU CE certificates and can be sold and used in mainland Europe and in countries and regions with recognized CE certificates.




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