√ The half-life is 90-120 minutes. In vitro stability, positive predictive value, and anti-drug interference effects are better than BNP. NT-proBNP is more sensitive than BNP in detecting early or mild heart failure
√ Low sample requirements: whole blood can be processed without centrifugation
√ Equipped with special dropper consumables, more suitable for clinical operation scenarios
√ Used to distinguish cardiogenic and pulmonary dyspnea
√ Used to assess the degree of heart failure and predict the survival rate of patients with acute decompensated heart failure
ICU, CCU, Respiratory Medicine, Emergency Department, Cardiology, Emergency vehicle, Nursing home, Ambulance
1.Emdin M, Passino C, Prontera C, et al. Comparison of brain natriuretic peptide (BNP) and amino-terminal proBNP for early diagnosis of heart failure[J].Clin Chem,2007,53:1289- 1297.
2.Januzzi JL, Camargo C, Anwaruddin S, et al. The N-terminal pro-BNP investigation of dysp-nea in the Emergency Department (PRIDE) study[J].Am J Cardiol,2005,95:948-954.
3.Lan lan Wang, Bei Cai, Xing bin Liu, De jia Huang, Jiang tao Tang, Li xin Li. Clinical application and evaluation of N-terminal pro-Brain natriuretic peptide quantitative detection in heart failure laboratory diagnosis. Chin J Lab Med [J],January 2006, Vol 9, No.1.
NT-proBNP is a polypeptide mainly comes from ventricle. Cardiomyocytes synthesize a pre-propeptide preproBNP with 134 amino acids, which is split into a signal peptide and a propeptide (proBNP with 108 amino acids). During secretion from the cardiomyocytes, proBNP is split in a ratio of 1:1 into a physiologically active C-terminal fragment BNP (with 32 amino acids) and a biologically inactive N-terminal fragment NT-proBNP (with 76 amino acids). In physiologically, 70% of NT-proBNP is secreted by ventricle because of the large mass of ventricle. Aside from ventricle, NT-proBNP is also secreted by other organs such as brain, kidney, aorta and adrenal gland. However the level is far less than cardiac.It was advocated as a beneficial biomarker for evaluating HF by the American Association for Clinical Chemistry in 2007 and is allowed to be used for diagnosis and evaluation of HF and ACS by FDA. There is also evidence suggests that NT-proBNP has prognostic value in evaluating the increase of risk of cardiovascular disease and the mortality of stable coronary artery disease[1-3].
1.We are based in Guangdong, China, start from 2021,sell to Africa(30.00%),South Asia(15.00%),Mid East(10.00%),Domestic Market(10.00%),North America(5.00%),South America(5.00%),Eastern Europe(5.00%),Southeast Asia(5.00%),Oceania(5.00%),Eastern Asia(5.00%),Western Europe(5.00%),Central America(5.00%),Northern Europe(5.00%),Southern Europe(5.00%). There are total about 51-100 staffs in our office.
2. How can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.What can you buy from us?
Test kit,In Vitro Diganositc,Disposable Samplers,Rapid test kits,Swab
4. Why should you buy from us not from other suppliers?
We focus on producing virus nucleic acid detection kits, Disposable samplers, IGG/IGM rapid test kit, PCR test kit etc.The products approved CE, FDA, SGS, ISO13485.More than 200 staffs, 10 production line.
5. What services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW；
Accepted Payment Currency:USD,EUR,HKD,CNY;
Accepted Payment Type: T/T,Credit Card,PayPal, Western Union,Escrow;
6.Can I have samples of this goods to test the quality?
Yes, free sample is available.
7.What's the delivery time and can you lower the price?
It depends on your order. The delivery time is within 3-4 days. If you have large quantities,the price and delivery time can be negotiable.
8.Can I customize the packaging and the logo?
Yes, we could offer customized logo for you.
9.What's the shipping method?
We often use DHL, FedEx, UPS, TK,EK,LH to ship our products.
10. The PCR test kit is required to be stored at a temperature between -25 degrees Celsius and -15 degrees Celsius. How did you do it?
Most of our PCR detection reagents are transported in an incubator, and the temperature can be maintained at -20 degrees Celsius for about 12 days, which can fully meet the general air transportation time limit.