Technical Specifications
Product Advantage
The window period is earlier than CRP, can reflect the infection quickly;
The half-life is shorter than CRP and PCT, It can timely assess the effectiveness of the drug, and suggest lowering the dose or stopping the drug to avoid overtreatment.
Clinical Significance
Interleukin-6 (IL-6) has important roles in both innate and adaptive immunity. As part of the innate immune system, IL-6 acts on hepatocytes to induce expression of C-reactive protein (CRP), fibrinogen, and serum amyloid A, also known as the acute phase response.
Concentrations of IL-6 are elevated in patients with infection, sepsis, and septicemia. In addition, IL-6 concentrations appear to correlate with severity of sepsis, as defined by clinical and laboratory parameters. Elevations in IL-6 also appear to be associated with more localized infections, such as prosthetic joint infections (PJI).A recent meta-analysis demonstrated that IL-6 had improved diagnostic accuracy for PJI compared to CRP, erythrocyte sedimentation rate (ESR), and white blood cell counts. IL-6 is also elevated in numerous chronic inflammatory disorders, including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), ankylosing spondylitis (AS), and inflammatory bowel disease (IBD). There is evidence that IL-6 is involved in the pathogenesis of certain chronic inflammatory disorders. Tocilizumab, an antibody that blocks IL-6 function by binding to the IL-6 receptor, has been approved for the treatment of RA. In a randomized trial, 50% to 60% of patients receiving tocilizumab and methotrexate showed improvement in clinical signs and symptoms of RA, compared to only 25% in patients receiving methotrexate alone.
Product Description
- Interleukin 6 (IL-6) is an interleukin that acts as both a pro inflammatory cytokine and an anti-inflammatory myokine. osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.
FAQ
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1.We are based in Guangdong, China, start from 2021,sell to Africa(30.00%),South Asia(15.00%),Mid East(10.00%),Domestic Market(10.00%),North America(5.00%),South America(5.00%),Eastern Europe(5.00%),Southeast Asia(5.00%),Oceania(5.00%),Eastern Asia(5.00%),Western Europe(5.00%),Central America(5.00%),Northern Europe(5.00%),Southern Europe(5.00%). There are total about 51-100 staffs in our office.
2. How can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.What can you buy from us?
Test kit,In Vitro Diganositc,Disposable Samplers,Rapid test kits,Swab
4. Why should you buy from us not from other suppliers?
We focus on producing virus nucleic acid detection kits, Disposable samplers, IGG/IGM rapid test kit, PCR test kit etc.The products approved CE, FDA, SGS, ISO13485.More than 200 staffs, 10 production line.
5. What services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW；
Accepted Payment Currency:USD,EUR,HKD,CNY;
Accepted Payment Type: T/T,Credit Card,PayPal, Western Union,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,French,Russian,Korean
6.Can I have samples of this goods to test the quality?
Yes, free sample is available.
7.What's the delivery time and can you lower the price?
It depends on your order. The delivery time is within 3-4 days. If you have large quantities,the price and delivery time can be negotiable.
8.Can I customize the packaging and the logo?
Yes, we could offer customized logo for you.
9.What's the shipping method?
We often use DHL, FedEx, UPS, TK,EK,LH to ship our products.
10. The PCR test kit is required to be stored at a temperature between -25 degrees Celsius and -15 degrees Celsius. How did you do it?
Most of our PCR detection reagents are transported in an incubator, and the temperature can be maintained at -20 degrees Celsius for about 12 days, which can fully meet the general air transportation time limit.
